HBM
ExoTEST™ for Overall Exosome capture and quantification from human SERUM | RTK-POS
- SKU:
- HBM-RTK-POS
- UPC:
- MPN:
- Availability:
- 5 to 7 Days Shipment
- Shelf Life:
- 24 months
Description
1 Review
-
5 Easy
Posted by Antonio Chiesi, MD on 25th Jan 2023
ExoTEST ELISAs are for quantitative and qualitative analysis of exosomes and exosomes quantification and characterization from small amount of human biological fluids or cell media Identify exosomes released by cancer cells in the plasma and urine of tumor patients in various disease conditions. ExoTEST consists of 1 ELISA plate pre-coated with proprietary pan-exosome antibodies enabling specific capture of exosomes from different biological samples, including cell culture supernatants and human biological fluids. Quantification and characterization of exosomal proteins is subsequently performed using appropriate detection antibodies against exosome associated antigens that can be for either generic or cell/tissue-specific exosomes. Lyophilized Exosome Standards, charcterized for protein content and particle number (NTA) allow the quantification of unknown sample by a standard calibration curve. About Exosomes Exosomes are small endosome derived lipid nanoparticles (50-120 nm) actively secreted by exocytosis by most living cells. Exosome release occurs either constitutively or upon induction, under both normal and pathological conditions, in a dynamic, regulated and functionally relevant manner. Both amount and molecular composition of released exosomes depend on the state of a parent cell. Exosomes have pleiotropic physiological and pathological functions and an emerging role in diverse pathological conditions such as cancer, infectious and neurodegenerative diseases
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