EV-Entry System for Exosome Delivery (5 rxn)
- Usually Shipped in 5 Working Days
- 5 reactions
- Shipping Temperature:
- Blue Ice/ Dry Ice
EV-Entry System for Exosome Delivery (5 rxn) . Cat# EVEN105A. Supplier: SBI System Biosciences
- Fast—the protocol takes less than one hour to complete
- Easy—just add the two reagents to your exosomes, incubate at room temperature, and add to recipient cells
- Powerful—greatly enhances the ability of exosomes and other EVs to deliver protein and RNA cargo to recipient cells
See how well the EV-Entry System enhances exosome-mediated cargo delivery
The EV-Entry System increases the efficiency of exosome-mediated delivery of proteins to target cells.
In Figure 1, Exo-Green is used to label exosomal proteins, and then EV-Entry enhanced transfer of Exo-Green-labeled exosomal proteins to recipient cells is monitored using fluorescence microscopy. In Figure 2, enhanced transfer of a specific exosomal protein—XPack-Luciferase (Cat.# XPAK732PA-1)—is shown. In both cases, the EV-Entry System increases the amount of cargo delivered.
The EV-Entry System also increases the efficiency of RNA cargo delivery.
In Figure 3, XMIR Texas Red-labeled Positive Control RNA Oligos (Cat.# XMIR-POS) are used to label exosomes and then EV-Entry enhanced transfer of the XMIR Texas Red-labeled RNA Oligo to recipient cells is monitored using fluorescence microscopy. As with the delivery of protein cargo, the EV-Entry System improves the efficiency of exosome-mediated delivery of RNAs.